Abstract

M Chilvers and P Black have nothing to disclose.

S Tian, G Marigowda, M Bsharat, C Hug are employees of Vertex Pharmaceuticals and may hold stock and/or stock options in the company.

M Solomon reports involvement in clinical trials with Vertex Pharmaceuticals. (sponsored the clinical trial, no money directly to PI)

M Rosenfeld reports that her institution has received funding from Vertex Pharmaceuticals for research on which she is an investigator. She also has served as a consultant for Vertex Pharmaceuticals.

G Sawicki reports personal fees from Vertex Pharmaceuticals outside the submitted work. (advisory boards)

J Hoppe reports grant funding from the Cystic Fibrosis Foundation outside the submitted work.