Introduction and Objectives Recent works shown that it was possible to predict COPD exacerbation based on monitoring of simple parameters, such as an increase of the breathing rate in spontaneous ventilation or under non-invasive ventilation. Continuous breathing rate monitoring of COPD patients could be, by consequence, a pertinent way to follow their state of health, or even to alert for exacerbation situation. We aim to validate the breathing rate measurement of a tele-monitoring solution (TeleOx, SRETT, Boulogne-Billancourt, France) on COPD patients under long term oxygen therapy, as a first step towards this perspective.

Methods Breathing rates of COPD patient under long term oxygen therapy were recorded over a night, simultaneously by TeleOx and by a reference polygraph (Nox T3, Nox Medical Inc. Reykjavik, Iceland). A median breathing rate was extracted every 5 min by TeleOx and compared to the exact same measurement from the reference polygraph. The agreement between the two methods is considered using Passing-Bablok regression on the measured breathing rate points set.

Results Passing-Bablok regression on 1099 measurement points coming from 14 representative patients, comparing Results from TeleOx and reference polygraph gives, within a confident interval of 95%, a slope b within [0.976; 1.000] and an intercept a within [−0.217; 0.325].

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Abstract P66 Figure 1

Comparison of breathing rate (BR) measurement. Results by TeleOx and polygraph, using Passing-Bablok regression on a set of 1099 valid measurement points. BR measurements by TeleOx and polygraph are materialised in red points. Passing-Bablok regression line is presented in continuous blue line. Identity (red dashed line) and uncertainty envelop (blue) are presented as a guide for the lectors.

Discussion The connected tele-monitoring device TeleOx, is capable of measuring the breathing rate of COPD subjects under long term oxygen therapy in excellent agreement with a reference polygraph. It opens encouraging e-medecin perspectives for this patient population.