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Original Article
Rapid decline in lung function is temporally associated with greater metabolically active adiposity in a longitudinal study of healthy adults
  1. Maan Moualla1,
  2. Clifford Qualls2,
  3. Alexander Arynchyn3,
  4. Bharat Thyagarajan4,
  5. Ravi Kalhan5,
  6. Lewis J Smith5,
  7. John J Carr6,
  8. David R Jacobs7,
  9. Akshay Sood1
  1. 1 Department of Medicine, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
  2. 2 Office of Research, Clinical Translational Science Center, University of New Mexico, Albuquerque, New Mexico, USA
  3. 3 Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
  4. 4 University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, Minnesota, USA
  5. 5 Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
  6. 6 Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA
  7. 7 Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
  1. Correspondence to Dr Akshay Sood, Department of Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, Albuquerque, NM 87131, USA; asood{at}salud.unm.edu

Footnotes

  • Contributors AS, MM, BT, RK, LJS and DRJ made substantial contributions to the conception or design of the work, and CQ, JJC and AA made substantial contributions to the acquisition, analysis or interpretation of data for the work. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA made substantial contribution towards drafting the work or revising it critically for important intellectual content. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA provided the final approval of the version to be published. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The Coronary Artery Risk Development in Young Adults Study (CARDIA) is conducted and supported by the National Heart, Lung, and Blood Institute (NHLBI) in collaboration with the University of Alabama at Birmingham (HHSN268201300025C & HHSN268201300026C), Northwestern University (HHSN268201300027C and R01 HL122477), University of Minnesota (HHSN268201300028C), Kaiser Foundation Research Institute (HHSN268201300029C), and Johns Hopkins University School of Medicine (HHSN268200900041C). CARDIA is also partially supported by the Intramural Research Program of the National Institute on Aging (NIA) and an intra,agency agreement between NIA and NHLBI (AG0005). This manuscript has been reviewed by CARDIA for scientific content.

  • Competing interests None declared.

  • Ethics approval CARDIA study was approved by each of the four participating institutions.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Additional unpublished data are available on request from the CARDIA Study Publications and Presentations Committee.

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Footnotes

  • Contributors AS, MM, BT, RK, LJS and DRJ made substantial contributions to the conception or design of the work, and CQ, JJC and AA made substantial contributions to the acquisition, analysis or interpretation of data for the work. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA made substantial contribution towards drafting the work or revising it critically for important intellectual content. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA provided the final approval of the version to be published. AS, MM, BT, RK, LJS, DRJ, CQ, JJC and AA agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The Coronary Artery Risk Development in Young Adults Study (CARDIA) is conducted and supported by the National Heart, Lung, and Blood Institute (NHLBI) in collaboration with the University of Alabama at Birmingham (HHSN268201300025C & HHSN268201300026C), Northwestern University (HHSN268201300027C and R01 HL122477), University of Minnesota (HHSN268201300028C), Kaiser Foundation Research Institute (HHSN268201300029C), and Johns Hopkins University School of Medicine (HHSN268200900041C). CARDIA is also partially supported by the Intramural Research Program of the National Institute on Aging (NIA) and an intra,agency agreement between NIA and NHLBI (AG0005). This manuscript has been reviewed by CARDIA for scientific content.

  • Competing interests None declared.

  • Ethics approval CARDIA study was approved by each of the four participating institutions.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Additional unpublished data are available on request from the CARDIA Study Publications and Presentations Committee.

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