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  • S109 Targeting the prostacyclin pathway in the treatment of connective tissue disease associated pulmonary arterial hypertension (PAH): insights from the randomised controlled griphon trial with selexipag

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Declarations of Interest
S109 Targeting the prostacyclin pathway in the treatment of connective tissue disease associated pulmonary arterial hypertension (PAH): insights from the randomised controlled griphon trial with selexipag

Abstract

The GRIPHON study was sponsored by Actelion Pharmaceuticals Ltd.

G Coghlan: Consulting fees: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, GenenTech, United Therapeutics. Speaker’s honoraria and research grants: Actelion Pharmaceuticals Ltd, GlaxoSmithKline, Bayer HealthCare, United Therapeutics.

S Gaine: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, United Therapeutics, Novartis, Pfizer. Steering Committee membership: Actelion Pharmaceuticals Ltd, GlaxoSmithKline, United Therapeutics, Novartis.

R Channick: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, United Therapeutics. Steering Committee membership: Actelion Pharmaceuticals Ltd. L Di Scala: Employee Actelion Pharmaceuticals Ltd.

N Galié: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, Pfizer. Steering Committee membership: Actelion Pharmaceuticals Ltd.

HA Ghofrani: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, Gilead Sciences Inc, GlaxoSmithKline, Merck & Co, Novartis Corporation, Pfizer Inc. Steering Committee membership: Actelion Pharmaceuticals Ltd, Bayer HealthCare, Gilead Sciences Inc, GlaxoSmithKline, Merck & Co, Novartis Corporation, Pfizer Inc.

MM Hoeper: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, Pfizer, Gilead Sciences. Steering Committee membership: Actelion Pharmaceuticals Ltd.

I Lang: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, Novartis Corporation, United Therapeutics. Steering Committee membership: Actelion Pharmaceuticals Ltd.

V McLaughlin: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, Gilead Sciences Inc, United Therapeutics, Ikaria, Novartis. Steering Committee membership: Actelion Pharmaceuticals Ltd, Bayer HealthCare, Gilead Sciences Inc, United Therapeutics, Ikaria.

R Preiss: Employee Actelion Pharmaceuticals Ltd. LJ Rubin: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Arena Pharmaceuticals, GeNO Pharmaceuticals, Lung Biotechnology, Gilead Sciences Inc, United Therapeutics. Steering Committee membership: Actelion Pharmaceuticals Ltd.

G Simonneau: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, Eli Lilly & Co, GlaxoSmithKline, Novartis Corporation, Pfizer Inc. Steering Committee membership: Actelion Pharmaceuticals Ltd. O Sitbon: Consulting fees/honoraria: Actelion Pharmaceuticals Ltd, Bayer HealthCare, GlaxoSmithKline, Pfizer Inc, United Therapeutics. Steering Committee membership: Actelion Pharmaceuticals Ltd.

https://doi.org/10.1136/thoraxjnl-2016-209333.465

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