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Tuberculosis: Clinical Aspects
P115 Screening outcomes of household contacts of multidrug-resistant tuberculosis patients in peshawar, pakistan
  1. A Javid1,
  2. MA Khan1,
  3. MA Khan2,
  4. S Mehreen1,
  5. A Basit1,
  6. RA Khan3,
  7. M Ihtesham1,
  8. I Ullah1,
  9. A Khan1,
  10. U Ullah1
  1. 1Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan
  2. 2Peshawar Medical College, Peshawar, Pakistan
  3. 3Kohat University of Science and Technology, Kohat, Pakistan

Abstract

Objective To assess the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TB patients.

Methods Close contacts of MDR-TB patients were traced in the cross-sectional study. Different clinical, radiological and bacteriological were performed to rule out the evidence of TB/MDR-TB.

Results Between January 2012 and December 2012, a total of 200 index MDR-TB patients were initiated on MDR-TB treatment, out of which home visit and contacts screening were conducted for 154 index cases. Of 610 contacts who could be studied, 41 (17.4%) were diagnosed with MDR-TB and 10 (4.2%) had TB. The most common symptoms observed were cough, chest pain and fever.

Conclusions The high incidence of MDR-TB among close contacts emphasise the need for effective contact screening programme of index MDR-TB cases in order to cut the chain of transmission of this disease.

References

  1. WHO. Multidrug resistant TB (MDR-TB): 2014 updated global report. Geneva: World Health OrganisationOrganization, 2014.

  2. WHO. Global tuberculosis report 2015. Geneva: World Health OrganisationOrganization, 2015.

  3. Khan MA, Mehreen S, Basit A, Khan RA, Javaid A. Predictors of poor outcomes among patients treated for multidrug-resistant tuberculosis at Tertiary Care Hospital in Pakistan. American-Eurasian J Toxicol Sci 2015;7(3):162–172.

https://doi.org/10.1136/thoraxjnl-2016-209333.258

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