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Monitoring on antitumour necrosis factor therapy
We screen people before starting on antitumour necrosis factor (anti-TNF) treatment for latent TB with interferon γ release assays before they start treatment, but what happens during treatment? (10.1136/annrheumdis-2014-205376) Out of 247 patients, 29% (20) converted for one test (nine Tuberculin skin test, seven T-SPOT, five QuantiFERON-TB Gold In Tube). One had definite TB contact. Eight were treated with isoniazid prophylaxis. It occurred more commonly on etanercept though this was not statistically significant. This has implications for future treatment and monitoring for those on anti-TNF therapy.
Influenza vaccine protects against influenza-associated pneumonia
The influenza jab is commonly blamed by people for admission to hospital with pneumonia and almost everything else. This study looked at the risk of influenza pneumonia in those who had received the influenza jab. Out of 2767 patients hospitalised due to pneumonia, 162 (5.9%) had swab confirmed influenza (doi:10.1001/jama.2015.12160). Of those with influenza-associated pneumonia, 28 (17%) were vaccinated; in the controls (influenza negative …
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