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  • Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia

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Respiratory infection
Original article
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia

Authors

  • Luke Hatchwell Department of Experimental & Translational Respiratory Medicine, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Adam Collison Department of Experimental & Translational Respiratory Medicine, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Jason Girkin Department of Experimental & Translational Respiratory Medicine, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Kristy Parsons Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Junyao Li Department of Experimental & Translational Respiratory Medicine, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Norman Bethune Medical Science Centre, Jilin University, Jilin, Changchun, China PubMed articlesGoogle scholar articles
  • Jie Zhang Norman Bethune Medical Science Centre, Jilin University, Jilin, Changchun, China PubMed articlesGoogle scholar articles
  • Simon Phipps The School of Biomedical Sciences, University of Queensland, Queensland, Queensland, Australia PubMed articlesGoogle scholar articles
  • Darryl Knight Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Nathan W Bartlett Airway Disease Infection Section, National Heart and Lung Institute, Medical Research Council & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, Norfolk Place, London, UK PubMed articlesGoogle scholar articles
  • Sebastian L Johnston Airway Disease Infection Section, National Heart and Lung Institute, Medical Research Council & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, Norfolk Place, London, UK PubMed articlesGoogle scholar articles
  • Paul S Foster Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Peter A B Wark Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Joerg Mattes Department of Experimental & Translational Respiratory Medicine, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Priority Research Centre for Asthma and Respiratory Diseases, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia Department of Paediatric Respiratory and Sleep Medicine, Newcastle Children's Hospital, Newcastle, New South Wales, Australia PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Joerg Mattes, Department of Paediatric Respiratory and Sleep Medicine, Newcastle Children's Hospital, Locked Bag 1, Newcastle, NSW 2305, Australia; joerg.mattes{at}newcastle.edu.au
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Citation

Hatchwell L, Collison A, Girkin J, et al
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia
Thorax 2015;70:854-861.

Publication history

  • Received March 25, 2014
  • Revised April 27, 2015
  • Accepted May 15, 2015
  • First published June 24, 2015.
Online issue publication 
September 01, 2022

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