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Audit, research and guideline update
The Study Team for Early Life Asthma Research (STELAR) consortium ‘Asthma e-lab’: team science bringing data, methods and investigators together
  1. Adnan Custovic1,
  2. John Ainsworth2,
  3. Hasan Arshad3,4,5,
  4. Christopher Bishop6,
  5. Iain Buchan2,
  6. Paul Cullinan7,
  7. Graham Devereux8,
  8. John Henderson9,
  9. John Holloway4,
  10. Graham Roberts3,5,10,
  11. Steve Turner8,
  12. Ashley Woodcock1,
  13. Angela Simpson1
  1. 1Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK
  2. 2Centre for Health Informatics, Institute of Population Health, University of Manchester, Manchester, UK
  3. 3David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
  4. 4Clinical and Experimental Sciences Academic Unit, University of Southampton Faculty of Medicine, Southampton, UK
  5. 5NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK
  6. 6Microsoft Research Cambridge, Cambridge, UK
  7. 7Imperial College, London, UK
  8. 8Child Health, University of Aberdeen, Aberdeen, UK
  9. 9School of Social and Community Medicine, University of Bristol, Bristol, UK
  10. 10Human Developmental and Health Academic Unit, University of Southampton Faculty of Medicine, Southampton, UK
  1. Correspondence to Professor Adnan Custovic, University of Manchester, University Hospital of South Manchester, Manchester M23 9LT, UK; adnan.custovic{at}manchester.ac.uk

Abstract

We created Asthma e-Lab, a secure web-based research environment to support consistent recording, description and sharing of data, computational/statistical methods and emerging findings across the five UK birth cohorts. The e-Lab serves as a data repository for our unified dataset and provides the computational resources and a scientific social network to support collaborative research. All activities are transparent, and emerging findings are shared via the e-Lab, linked to explanations of analytical methods, thus enabling knowledge transfer. eLab facilitates the iterative interdisciplinary dialogue between clinicians, statisticians, computer scientists, mathematicians, geneticists and basic scientists, capturing collective thought behind the interpretations of findings.

  • Asthma
  • Asthma Epidemiology
  • Paediatric asthma

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/

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