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Correspondence
Radiographic patterns of acute chest syndrome
  1. Armand Mekontso Dessap
  1. Correspondence to Professor Armand Mekontso Dessap, AP-HP, Hôpitaux Universitaires Henri Mondor, DHU A-TVB, Service de Réanimation Médicale; UPEC, Faculté de Médecine, Groupe de recherche clinique CARMAS; 51 Av Mal deLattre de Tassigny, Créteil, Cedex 94 010, France; armand.dessap{at}hmn.aphp.fr

https://doi.org/10.1136/thoraxjnl-2015-207088

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    Dear editor,

    We read with great interest the year in review 2014 by Andy Bush and Ian Pavord1 on paediatric and adult clinical studies. While discussing our paper,2 the reviewer seems to have misinterpreted our results when saying that consolidation is more severe in the apex of adult sickle cell disease patients with acute chest syndrome. In fact, CT and bedside chest radiography showed that lung parenchyma was increasingly consolidated from apex to base.2 This distribution is in accordance with previous studies,3 ,4 but may vary with age, with young children having more upper and middle lobe disease, contrarily to adult patients.3

    References

    1. ↵
      1. Bush A,
      2. Pavord I
      . Year in review 2013: paediatric and adult clinical studies. Thorax 2015;69:309–11. doi:10.1136/thoraxjnl-2014-205222
      OpenUrl
    2. ↵
      1. Mekontso Dessap A,
      2. Deux JF,
      3. Habibi A, et al
      . Lung imaging during acute chest syndrome in sickle cell disease: computed tomography patterns and diagnostic accuracy of bedside chest radiograph. Thorax 2014;69:144–51. doi:10.1136/thoraxjnl-2013-203775
      OpenUrlAbstract/FREE Full Text
    3. ↵
      1. Vichinsky EP,
      2. Styles LA,
      3. Colangelo LH, et al
      . Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease. Blood 1997;89:1787–92.
      OpenUrlAbstract/FREE Full Text
    4. ↵
      1. Mekontso Dessap A,
      2. Deux JF,
      3. Abidi N, et al
      . Pulmonary artery thrombosis during acute chest syndrome in sickle cell disease. Am J Respir Crit Care Med 2011;184:1022–9. doi:10.1164/rccm.201105-0783OC
      OpenUrlCrossRefPubMedWeb of Science
    View Abstract

    Footnotes

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.