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Chest clinic
Audit, research and guideline update
Developmental determinants in non-communicable chronic diseases and ageing
  1. J Bousquet1,2,3,4,
  2. J M Anto4,5,6,7,8,
  3. K Berkouk9,
  4. P Gergen10,
  5. J Pinto Antunes11,
  6. P Augé3,12,
  7. T Camuzat3,13,
  8. J Bringer3,14,
  9. J Mercier3,15,16,
  10. N Best3,17,
  11. R Bourret3,18,
  12. M Akdis4,19,
  13. S H Arshad20,
  14. A Bedbrook3,
  15. C Berr3,21,
  16. A Bush22,
  17. G Cavalli3,23,
  18. M A Charles24,
  19. F Clavel-Chapelon25,
  20. M Gillman26,27,
  21. D R Gold28,
  22. M Goldberg29,
  23. J W Holloway30,
  24. P Iozzo31,
  25. S Jacquemin3,32,
  26. C Jeandel3,33,
  27. F Kauffmann4,34,
  28. T Keil4,35,36,
  29. G H Koppelman4,37,
  30. S Krauss-Etschmann38,
  31. D Kuh39,
  32. S Lehmann3,40,
  33. K C Lodrup Carlsen4,41,
  34. D Maier4,42,
  35. M Méchali23,
  36. E Melén4,43,
  37. J P Moatti44,
  38. I Momas4,45,46,
  39. P Nérin3,47,
  40. D S Postma4,48,
  41. K Ritchie3,49,
  42. J M Robine3,50,51,52,
  43. B Samolinski53,
  44. V Siroux4,54,55,56,
  45. P E Slagboom57,58,
  46. H A Smit4,59,
  47. J Sunyer4,5,6,7,8,
  48. R Valenta4,60,
  49. P Van de Perre61,
  50. J M Verdier3,62,63,64,
  51. M Vrijheid5,7,8,
  52. M Wickman4,43,
  53. P Yiallouros65,
  54. M Zins66
  1. 1University Hospital, Montpellier, France
  2. 2Inserm U 1168, Paris, France
  3. 3Contre les Maladies Chroniques pour un Vieillissement Actif en Languedoc Roussillon, Site de Référence de l'EIP on AHA, Montpellier, France
  4. 4MeDALL, Mechanisms of the Development of Allergy, FP7, Amsterdam, Groningen, the Netherlands
  5. 5Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain
  6. 6IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
  7. 7Universitat Pompeu Fabra (UPF), Barcelona, Spain
  8. 8CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
  9. 9Deputy Head of Unit for Medical Research and the Challenge of Ageing, DG Research & Innovation, European Commission, Brussels, Belgium
  10. 10National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA
  11. 11European Commission, Directorate General for Health and Consumers, Brussels, Belgium
  12. 12University Montpellier 1, France
  13. 13Région Languedoc Roussillon, France
  14. 14Montpellier Medical School, France
  15. 15Department of Physiology, Montpellier University Hospital, France
  16. 16University Montpellier 1, France
  17. 17Nimes University Hospital, France
  18. 18Montpellier University Hospital, France
  19. 19Swiss Institute of Allergy and Asthma Research (SIAF), Davos and University of Zurich, Switzerland
  20. 20David Hide Asthma and Allergy Research Centre, Isle of Wight, UK
  21. 21Inserm, Research Unit U1061, University Montpellier I, Montpellier, France
  22. 22Department of Paediatric Respiratory Medicine, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK
  23. 23Institute of Human Genetics, CNRS, Montpellier, France
  24. 24Equipe 10 UMR Inserm-Université Paris-Sud (Centre de recherche en Epidémiologie et Santé des Populations, CESP), Villejuif, France
  25. 25Nutrition, Hormones and Women's Health Team, INSERM UMR-S 1018, Paris-South University, Villejuif, France
  26. 26Obesity Prevention Program, Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA
  27. 27Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
  28. 28Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, and Harvard School of Public Health, UK
  29. 29Population-Based Epidemiological Cohorts, INSERM-UVSQ UMS 011, Villejuif, France
  30. 30Human Development & Health, Faculty of Medicine, University of Southampton, Southampton, UK
  31. 31Institute of Clinical Physiology, National Research Council (CNR), Pisa, Italy
  32. 32Horiba, Montpellier, France
  33. 33Department of Geriatrics, University Hospital, Montpellier, France
  34. 34CESP—Team of Respiratory and Environmental Epidemiology INSERM UMR-S1018, University Paris-Sud, Villejuif, France
  35. 35Institute of Social Medicine, Epidemiology and Health Economics, Charité—Universitätsmedizin, Berlin, Germany
  36. 36Institute for Clinical Epidemiology and Biometry, Julius Maximilian University of Wuerzburg, Germany
  37. 37Department of Pediatric Pulmonology and Pediatric Allergology, University of Groningen, University Medical Center Groningen, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands
  38. 38Comprehensive Pneumology Center, Ludwig Maximilians University and Helmholtz Zentrum Muenchen, Member of the German Research Center for Lung Research, Großhadern, Germany
  39. 39MRC Unit for Lifelong Health and Ageing at UCL, London, UK
  40. 40Institut de Médecine Régénératrice et de Biothérapie (I.M.R.B.), University Hospital, INSERM U1040, Montpellier, France
  41. 41Department of Paediatrics, University of Oslo and Oslo University Hospital, Oslo, Norway
  42. 42Biomax Informatics AG, Planegg, Germany
  43. 43Institute of Environmental Medicine, Karolinska Institutet and Sachs’ Children's Hospital, Stockholm, Sweden
  44. 44Aix-Marseille University (AMU), Research Unit 912 AMU/INSERM/IRD Social and Economic Sciences Applied to Health (SESSTIM), France
  45. 45Department of Public health and biostatistics, Descartes University, Paris, France
  46. 46Municipal Department of social action, childhood, and health, Paris, France
  47. 47SATT AxLR, Montpellier, France
  48. 48Department of Pulmonology, University Medical Center Groningen, University of Groningen, GRIAC Research Institute, Groningen, The Netherlands
  49. 49Inserm U1061 Neuropsychiatry, Montpellier and Faculty of Medicine, Imperial College London, London, UK
  50. 50Inserm Research Unit 988, Paris, France
  51. 51Inserm Research Unit 710, Montpellier, France
  52. 52Ecole Pratique des Hautes Etudes (EPHE), Paris, France
  53. 53Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland
  54. 54Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, University Grenoble Alpes, IAB, Grenoble, France
  55. 55Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, INSERM, IAB, Grenoble, France
  56. 56Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, CHU de Grenoble, IAB, Grenoble, France
  57. 57Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands
  58. 58Consortium for Healthy Aging, Leiden University Medical Center, Leiden, the Netherlands
  59. 59Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands
  60. 60Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
  61. 61University Hospital and INSERM U 1058, Montpellier, France
  62. 62EPHE, Section des Sciences de la Vie et de la Terre, Paris, France
  63. 63UMR S 710, University Montpellier 2, Montpellier, Paris, France
  64. 64Institut Transdisciplinaire d'Etudes du Vieillissement, Montpellier, France
  65. 65Cyprus International Institute for Environmental & Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus
  66. 66Director of Population-Based Epidemiological Cohorts, INSERM-UVSQ UMS 011, Villejuif, France
  1. Correspondence to Professor Jean Bousquet, 273 av d'Occitanie, Montpellier 34090, France; fabienne.portejoie{at}gmail.com

Abstract

Prenatal and peri-natal events play a fundamental role in health, development of diseases and ageing (Developmental Origins of Health and Disease (DOHaD)). Research on the determinants of active and healthy ageing is a priority to: (i) inform strategies for reducing societal and individual costs of an ageing population and (ii) develop effective novel prevention strategies. It is important to compare the trajectories of respiratory diseases with those of other chronic diseases.

  • Asthma
  • COPD ÀÜ Mechanisms
  • Paediatric asthma

https://doi.org/10.1136/thoraxjnl-2014-206304

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