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Airway anatomy as a risk factor of COPD
  1. Plamen Bokov1,2,
  2. Christophe Delclaux1,2,3
  1. 1AP-HP, Hôpital européen Georges-Pompidou, Service de Physiologie—Clinique de la Dyspnée, Paris, France
  2. 2Faculté de médecine, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
  3. 3CIC 9201 Plurithématique, Hôpital Européen Georges Pompidou, Paris, France
  1. Correspondence to Professor Christophe Delclaux, Physiologie Respiratoire—Clinique de la Dyspnée, Hôpital Européen Georges-Pompidou, 20, Rue Leblanc; Paris 75015, France; christophe.delclaux{at}

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We read with interest the study of Smith and colleagues,1 because besides their counterintuitive result of thinner airways in COPD, another important result is their smaller airway lumen areas of the whole bronchial tree. Their Table E4 shows that adjusted values of areas for confounding factors are significantly reduced from trachea to the sixth airway generation in COPD.

Based on theoretical arguments, the whole human bronchial tree anatomy can be described by only two factors: the tracheal cross-sectional area and the …

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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