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Response to: ‘On the TIDES study’, by Quittner et al
  1. Mandy Bryon1,
  2. A Kevin Webb2
  1. 1Great Ormond St Hospital for Children NHS Trust, London, UK
  2. 2Manchester Adult cystic fibrosis Unit, Wythenshawe Hospital, University Hospitals, Manchester, UK
  1. Correspondence to Dr Mandy Bryon, Great Ormond St Hospital for Children NHS Trust, London WC1N 3JH, UK;

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Dear editors

In response to the correspondence by Quittner et al, we have the following comments. It must be stated that we think your The International Depression Epidemiological Study (TIDES) paper1 has merit, and we commend any endeavours to highlight the mental health issues of people with cystic fibrosis (CF) and improvements in psychosocial service provision. The editorial has no intention of minimising the extent of the problem, quite the opposite. Your publication (and further correspondence) reports on two different issues: first, the TIDES study, and second, the recommendations of the International Guidelines Committee on Mental Health (IGCMH) in CF. The second is dependent on the findings of the first. So, the TIDES paper has methodological weaknesses and inconsistencies between the various publications that have devolved from the study.2 ,3 The TIDES authors must be conscientious in the conclusions they draw and the level of clinical significance that is …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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