Article Text

Audit, research and guideline update
A UK-based resource to support the monitoring and safe use of anti-TB drugs and second-line treatment of multidrug-resistant TB
  1. J L Potter1,
  2. T Capstick2,
  3. W M Ricketts3,
  4. N Whitehead4,
  5. O M Kon5
  1. 1Department of Respiratory Medicine, Barts Health NHS Trust, London, UK
  2. 2Department of Medicines Management and Pharmacy Services, Leeds University Hospitals Trust, Leeds, UK
  3. 3Department of Respiratory Medicine, The Whittington Hospital, London, UK
  4. 4Department of Respiratory Medicine, Queen Alexandra Hospital, Portsmouth, UK
  5. 5Imperial College London, Chest and Allergy Clinic, London, UK
  1. Correspondence to Dr Jessica Louise Potter, Department of Respiratory Medicine, London Chest Hospital, Bonner Road, London E2 9JX, UK; Jessica.keal{at}, Jessica.potter{at}


Using the best available evidence and expert consensus, this document provides guidance for adverse effect monitoring in multidrug-resistant TB (MDR-TB). It includes recommendations for baseline tests, routine drug and toxicity monitoring guides as well as individual drug monographs for all drugs currently available in the UK to treat TB. These recommendations provide a structure through which healthcare professionals can better manage the complex drug regimens required for the treatment of MDR-TB; minimising the risk of adverse incidents and helping to improve patients’ tolerance, compliance and treatment completion.

  • Tuberculosis
  • Respiratory Infection
  • Drug reactions

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