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The randomised controlled trial (GLISTEN) by Frith et al1 showed significant improvements in trough FEV1, health-related quality of life and rescue medication when long-acting muscarinic antagonists (LAMA: as either tiotropium or glycopyrronium) were added to inhaled corticosteroid/long-acting beta-agonist (ICS/LABA: as fluticasone/salmeterol) in 773 patients with moderate-to-severe COPD (FEV1 57.2%) over 12 weeks. The authors concluded that this was the first …
Footnotes
Competing interests BL has received support to attend BTS and ERS from Boehringer Ingelheim and has also received payment for attending advisory boards from Boehringer Ingelheim, Chiesi and Teva. The Scottish Centre for Respiratory Research has received unrestricted education grant funding from Almirall, Teva and Chiesi. Scottish Centre for Respiratory Research has received support to attend ERS from Teva and Chiesi.
Provenance and peer review Not commissioned; internally peer reviewed.