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Mortality of patients with COPD participating in chronic disease management programmes: a happy end?
  1. I Peytremann-Bridevaux1,
  2. P Taffe1,
  3. B Burnand1,
  4. P O Bridevaux2,3,
  5. M A Puhan4
  1. 1Healthcare Evaluation Unit, Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland
  2. 2Centre Hospitalier du Valais Romand, Sion, Switzerland
  3. 3Division of Pulmonary Medicine, Geneva University Hospital, Geneva, Switzerland
  4. 4Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland
  1. Correspondence to Professor Isabelle Peytremann-Bridevaux, Institute of Social and Preventive Medicine, 10 route de la Corniche, Lausanne 1010, Switzerland; Isabelle.Peytremann-Bridevaux{at}


Background Concerns about increased mortality could question the role of COPD chronic disease management (CDM) programmes. We aimed at extending a recent Cochrane review to assess the effects of CDM on mortality in patients with COPD.

Methods Mortality data were available for 25 out of 29 trials identified in a COPD integrated care systematic review. Meta-analysis using random-effects models was performed, followed by subgroup analyses according to study length (3–12 months vs >12 months), main intervention component (exercise, self-management, structured follow-up) and use of an action plan.

Results The meta-analysis showed no impact of CDM on mortality (pooled OR: 1.00, 95% CI 0.79 to 1.28).

Conclusions These results do not suggest that CDM programmes expose patients with COPD to excessive mortality risk.

  • COPD epidemiology
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