You are here

Article Text

Article menu

Download PDFPDF

Miscellanea
Journal club
Dupilumab in persistent asthma with elevated eosinophil levels
Free
  1. Ruksha Bhadresha
  1. Correspondence to Dr Ruksha Bhadresha, FY2 East Sussex Healthcare NHS Trust, Conquest Hospital, The Ridge, St Leonards-on-Sea, East Sussex TN37 7RD, UK; ruksha.bhadresha{at}nhs.net

https://doi.org/10.1136/thoraxjnl-2013-204437

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Monoclonal antibodies are an effective treatment for a number of inflammatory autoimmune conditions, particularly those refractory to first-line medications. In asthma, airway inflammation may be associated with Th2 cell overactivity and raised eosinophils in up to 50% of cases. Th2 activation leads to the release of interleukin (IL)-13 and IL-4, which mediate their effects via receptors containing the IL-4 …

    View Full Text