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Case based discussion
A case report of subacute bronchial toxicity induced by an electronic cigarette
  1. José Hureaux1,2,3,4,
  2. Martine Drouet1,2,
  3. Thierry Urban1,2,3,4
  1. 1LUNAM Université, Angers, France
  2. 2CHU Angers, Département de Pneumologie, Oncologie et Allergologie, Angers, France
  3. 3INSERM UMR_S 1066 Micro et Nanomédecines Biomimétiques, Angers, France
  4. 4Université d'Angers, Equipe Pyver, Angers, France
  1. Correspondence to Dr José Hureaux, Département de Pneumologie, Centre Hospitalier Universitaire, 4, rue Larrey, Angers 49000, France; johureaux{at}chu-angers.fr

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José Hureaux (JH): I would like to present the case of a 43-year-old patient who presented with bronchial syndrome associated with deterioration of pulmonary function tests (PFTs) after starting to use an electronic cigarette. He had a history of primary lung adenocarcinoma with a documented isolated brain metastasis (stage pT3N0M1b) treated by stereotactic brain radiotherapy, right upper lobectomy and chemotherapy. The patient had been under surveillance for 7 months. This patient, an active smoker (45 pack-years) undergoing smoking cessation with the assistance of his general practitioner based on a reduction strategy accompanied by nicotine replacement therapy (21 mg patch), continued to smoke about 20 cigarettes a day. In order to completely stop smoking, he decided to try an electronic cigarette on the advice of a friend.

Thierry Urban (TU): Smoking cessation is useful in all patients operated for lung cancer, and must be encouraged. The e-cigarette provides nicotine via the inhaled route from which it is rapidly absorbed by a modality corresponding to the usual actions of smoking, while reducing the exposure of individuals to carcinogenic substances present in tobacco smoke. However, the real place of e-cigarettes in the therapeutic aid to smoking cessation is unknown.

JH: He purchased an e-cigarette (‘La dynamique’ by CIGARTEX) and two …

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Footnotes

  • Contributors Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; planning the work: JH, TU. Drafting the work or revising it critically for important intellectual content; conducting the work; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved; reporting the work: JH, MD, TU.

  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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