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Correspondences
COPD and IPF: it's all about regulation and balance
  1. Argyris Tzouvelekis1,
  2. Demosthenes Bouros2
  1. 1Division of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut, USA
  2. 2Department of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
  1. Correspondence to Dr Argyris Tzouvelekis, Division of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, 300 Cedar Street, TAC bld, New Haven, CT 06511, USA; atzouvelekis{at}yahoo.gr

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The dominant theory of Hippocrates was that of the four humours—that when the four humours were in balance health prevailed. Therefore, the main goal of the medical therapy was to restore humoral equilibrium. We read with great interest the article by Hou et al,1 where an imbalance between protective and detrimental subgroups of T regulatory (Treg) cells in patients with COPD is showed. On the contrary with previous studies reporting no significant differences in CD4 foxp3+ T cells between patients with COPD and smokers,2 …

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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