You are here

Article Text

Article menu
Download PDFPDF
Miscellanea
Journal club
A novel mechanism for MET and EGFR axis regulation in non-small cell lung cancer involving microRNA-27a and Sprouty2
  1. Omair Shariq
  1. Correspondence to Dr Omair Shariq, Department of Surgery, Chelsea and Westminster Hospital NHS Trust, 369 Fulham Road, London SW10 9NH, UK; omair.shariq{at}gmail.com

https://doi.org/10.1136/thoraxjnl-2013-204084

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Epidermal growth factor receptor (EGFR) and hepatocyte growth factor receptor (MET) are tyrosine kinase receptors that have been implicated in the pathogenesis of non-small cell lung cancer (NSLC). Sprouty2, a ubiquitously expressed protein, has been shown to upregulate EGFR and MET in several types of cancers. Conversely, microRNAs are small non-coding RNA molecules that regulate gene expression negatively, …

    View Full Text

    Footnotes

    • Competing interests None.

    • Provenance and peer review Not commissioned; internally peer reviewed.