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Rhinovirus and risk of childhood asthma
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Caliskan et al 1 report a significant interaction between genotype variants at the 17q21 locus and human rhinovirus (HRV) wheezing illness in early life leading to the development of childhood onset asthma. The authors studied the Childhood Origins of Asthma (COAST) and the Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth cohorts, as well as 100 adults. Genotype-specific effects of HRV stimulation on …
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Competing interests None.
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Provenance and peer review Not commissioned; internally peer reviewed.