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  • On-treatment platelet reactivity in patients with chronic obstructive pulmonary disease undergoing percutaneous coronary intervention

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Research letter
Research letter
On-treatment platelet reactivity in patients with chronic obstructive pulmonary disease undergoing percutaneous coronary intervention
  1. Gianluca Campo1,2,
  2. Rita Pavasini1,
  3. Alberto Pollina1,
  4. Matteo Tebaldi1,
  5. Roberto Ferrari1,2
  1. 1Department of Medical Sciences, Cardiovascular Institute, Azienda Ospedaliero-Universitaria S.Anna, Cona, Ferrara, Italy
  2. 2LTTA Center, Ferrara, Italy
  1. Correspondence to Dr Gianluca Campo, Department of Medical Sciences, Cardiovascular Institute, Azienda Ospedaliera Universitaria S. Anna, Via Aldo Moro, 8, Cona, (FE) 44124, Italy; cmpglc{at}unife.it

Abstract

Patients with chronic obstructive pulmonary disease (COPD) show a poor prognosis after myocardial infarction (MI) and percutaneous coronary intervention (PCI). We evaluated on-treatment platelet reactivity (PR) and several gene polymorphisms related to PR in 130 patients undergoing PCI with and without COPD. Those with concomitant COPD showed higher on-treatment PR values both at the time of PCI and 1 month after. This finding may contribute to explain the poor prognosis of COPD patients after MI and PCI.

  • COPD epidemiology

https://doi.org/10.1136/thoraxjnl-2013-203608

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