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https://doi.org/10.1136/thoraxjnl-2013-204765

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    We are now testing for EGFR mutations in order to aid the oncological treatment of lung cancer. This sometimes involves a need to obtain further tissue in order to test for the EGFR mutation. In this paper from Amsterdam the authors describe testing sputum for the EGFR mutation (Lung Cancer 2013;82:38–43). Sputum was tested in 10 patients with EGFR positive proven lung cancer and 10 patients with COPD, using DNA PCR. EGFR mutations were seen in 30–50% of the sputum samples of those with EGFR mutations.

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    Footnotes

    • Competing interests None.

    • Provenance and peer review Not commissioned; internally peer reviewed.