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S134 Activity monitoring in intensive care unit survivors: Assessing daily physical activity with objective outcome measures
  1. AS McNelly1,
  2. J Rawal1,
  3. P Chan1,
  4. N Hopkinson2,
  5. J Moxham 3,
  6. SDR Harridge 4,
  7. N Hart5,
  8. H Montgomery1,
  9. Z Puthucheary1
  1. 1Institute of Health and Human Performance, UCL, London, UK
  2. 2Royal Brompton Hospital, Imperial College, London, UK
  3. 3King’s College Hospital NHS Foundation Trust, London, UK
  4. 4Centre of Human and Aerospace Physiological Sciences, King’s College London, London, UK
  5. 5Lane Fox Clinical Respiratory Physiology Unit, Guy’s and St Thomas’ NHS Foundation Trust, London, UK


Introduction and Objectives Intensive care unit (ICU) survivors commonly report long-term functional disability and reduced daily physical activity (PA). This adversely impacts on their health-related quality of life (HRQL). We aimed to investigate the relationship between subjective and objective measures of PA in this patient group.

Methods Subjects were ICU survivors drawn from the 63 participants of the Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation (MUSCLE) study. All were over 16 years, invasively ventilated for > 48 hours with an ICU length of stay >7days. Objective (SenseWear Pro accelerometers, BodyMedia Inc, Pittsburgh, US) and self-reported subjective PA levels (HRQL SF-36 questionnaire, QualityMetric Inc, Lincoln, US) were measured.

Results At 18 months 20 pts had died; 17 were lost to follow-up, and 1 withdrew. 27 patients were studied (14 female) with a mean age ± SEM of 56.6 ± 3.6 years and a post-ICU discharge time of 576 ± 190d. SF-36 scores were lower than normal range scores. Age-adjusted (AA) mean steps/day correlated with norm-based physical component summary (PCS) SF-36 scores (Pearson's r = + 0.58;p < 0.01), but there was no correlation with the mental component summary scores ( Fig. 1). AA daily step variation showed positive associations with absolute levels of AA daily steps (r = + 0.85;p < 0.01), SF-36 physical function (PF) scores (r = + 0.62;p < 0.01), and prior working status (r = + 0.69;p < 0.01); and a negative association with chronic disease (r = -0.54;p < 0.01). Levels of AA daily steps contributed more to AA daily step variation than SF scores (r2 = 0.72, 0.38 respectively). Receiver Operator Characteristic analysis indicated that AA daily steps and PF scores are good (but non-significant) predictors for working post-ICU (0.88, 0.86 respectively; p > 0.05).

Abstract S134 Figure 1.

Correlations between Physical Function and Mental Component Summary SF-36 Scores against Physical Activity.

Conclusion This is the first report on the use of activity monitors in ICU survivors, and indicates that subjective and objective measures of PA are correlated. Such complementary data can be used to investigate functional disability in critical illness survivors. Both methods of assessing PA identified strong associations with health and socio-economic factors. Variation in step count, and specifically lack of variation in step count, may be more attributable to absolute step count than self-reported PF or chronic disease. Objective PA measures may offer advantages for monitoring post-ICU patients compared with subjective methods.

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