• Not Applicable

This study assesses whether oestradiol contributes to early mucoid pseudomonas colonisation and increased exacerbation frequency in female patients with cystic fibrosis (CF).

In vitro oestradiol induced more alginate production, defining mucoid conversion, at 3 days and 4 weeks compared with ethanol and testosterone, and more mucoid colonies were seen at 4 weeks following oestradiol culture. In …