Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

Alex R Horsley; Jane C Davies; Robert D Gray; Kenneth A Macleod; Jackie Donovan; Zelena A Aziz; Nicholas J Bell; Margaret Rainer; Shahrul Mt-Isa; Nia Voase; Maria H Dewar; Clare Saunders; James S Gibson; Javier Parra-Leiton; Mia D Larsen; Sarah Jeswiet; Samia Soussi; Yusura Bakar; Mark G Meister; Philippa Tyler; Ann Doherty; David M Hansell; Deborah Ashby; Stephen C Hyde; Deborah R Gill; Andrew P Greening; David J Porteous; J Alastair Innes; A Christopher Boyd; Uta Griesenbach; Steve Cunningham; Eric WFW Alton

doi:10.1136/thoraxjnl-2012-202538

Article info

PDF

PDF +
Supplementary
Material

Cystic fibrosis

Original article

Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

Free

Authors

Alex R Horsley UK Cystic Fibrosis Gene Therapy Consortium, London, UK University of Manchester and Manchester Adult Cystic Fibrosis Centre, University Hospitals South Manchester, Manchester, UK PubMed articles Google scholar articles
Jane C Davies UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Robert D Gray UK Cystic Fibrosis Gene Therapy Consortium, London, UK MRC/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, UK PubMed articles Google scholar articles
Kenneth A Macleod UK Cystic Fibrosis Gene Therapy Consortium, London, UK Royal Hospital for Sick Children, Edinburgh, UK PubMed articles Google scholar articles
Jackie Donovan UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Zelena A Aziz Department of Radiology, Royal Brompton Hospital, London, UK PubMed articles Google scholar articles
Nicholas J Bell UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Margaret Rainer UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Shahrul Mt-Isa Imperial Clinical Trials Unit, School of Public Health, Imperial College, London, UK PubMed articles Google scholar articles
Nia Voase UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Maria H Dewar UK Cystic Fibrosis Gene Therapy Consortium, London, UK Scottish Adult Cystic Fibrosis Service, Western General Hospital, Edinburgh, UK PubMed articles Google scholar articles
Clare Saunders UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
James S Gibson UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Javier Parra-Leiton UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Mia D Larsen UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Sarah Jeswiet UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Samia Soussi UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Yusura Bakar UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Mark G Meister Department of Radiology, Royal Brompton Hospital, London, UK PubMed articles Google scholar articles
Philippa Tyler Department of Radiology, Royal Brompton Hospital, London, UK PubMed articles Google scholar articles
Ann Doherty UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
David M Hansell Department of Radiology, Royal Brompton Hospital, London, UK PubMed articles Google scholar articles
Deborah Ashby Imperial Clinical Trials Unit, School of Public Health, Imperial College, London, UK PubMed articles Google scholar articles
Stephen C Hyde UK Cystic Fibrosis Gene Therapy Consortium, London, UK Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK PubMed articles Google scholar articles
Deborah R Gill UK Cystic Fibrosis Gene Therapy Consortium, London, UK Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK PubMed articles Google scholar articles
Andrew P Greening UK Cystic Fibrosis Gene Therapy Consortium, London, UK Scottish Adult Cystic Fibrosis Service, Western General Hospital, Edinburgh, UK PubMed articles Google scholar articles
David J Porteous UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
J Alastair Innes UK Cystic Fibrosis Gene Therapy Consortium, London, UK Scottish Adult Cystic Fibrosis Service, Western General Hospital, Edinburgh, UK PubMed articles Google scholar articles
A Christopher Boyd UK Cystic Fibrosis Gene Therapy Consortium, London, UK Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK PubMed articles Google scholar articles
Uta Griesenbach UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles
Steve Cunningham UK Cystic Fibrosis Gene Therapy Consortium, London, UK Royal Hospital for Sick Children, Edinburgh, UK PubMed articles Google scholar articles
Eric WFW Alton UK Cystic Fibrosis Gene Therapy Consortium, London, UK Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, UK PubMed articles Google scholar articles

Correspondence to Dr Christopher Boyd, Medical Genetics Section, Molecular Medicine Centre, University of Edinburgh, Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, UK; Chris.Boyd{at}ed.ac.uk; Dr Uta Griesenbach, Department of Gene Therapy, National Heart and Lung Institute, Imperial College, London, Manresa Road, London SW3 6LR, UK; u.griesenbach{at}imperial.ac.uk

View Full Text

Citation

Horsley AR, Davies JC, Gray RD, et al

Changes in physiological, functional and structural markers of cystic fibrosis lung disease with treatment of a pulmonary exacerbation

Thorax 2013;68:532-539.

Publication history

Received August 6, 2012
Revised January 11, 2013
Accepted January 16, 2013
First published February 9, 2013.

Online issue publication

May 08, 2013

Article Versions

Previous version (9 February 2013).
You are viewing the most recent version of this article.

Supplementary Data

This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

Files in this Data Supplement:

Data supplement 1 - Online supplement

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

Log in using your username and password

Main menu

Log in using your username and password

You are here

Authors

Citation

Publication history

Article Versions

Supplementary Data

Request permissions

Copyright information

Read the full text or download the PDF:

Log in using your username and password