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Correspondence
Author's response to Persson letter
  1. Sally Wenzel
  1. Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Asthma Institute, Pittsburgh, Pennsylvania, USA
  1. Correspondence to Dr Sally Wenzel, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Asthma Institute, 3459 Fifth Avenue, NW 528 Montefiore, Pittsburgh, Pennsylvania 15213, USA; wenzelse{at}upmc.edu

https://doi.org/10.1136/thoraxjnl-2012-202949

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    Dr Persson raises excellent points regarding the potential for epithelial cells to contribute to the clearance of eosinophils from tissue. We are in agreement that eosinophils can migrate from bone marrow to blood to submucosa to epithelium to lumen. However, the speed of the process, the role and response of each compartment, the stimulus for it and its overall control remain poorly understood. Dr Persson suggests that previous reports show an inverse relationship of tissue compared with luminal/epithelial eosinophils following …

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    Footnotes

    • Funding None.

    • Competing interests None.

    • Provenance and peer review Commissioned; internally peer reviewed.

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