I read with interest the study by Coleman et al 1 on lumen eotaxins and eosinophils, and epithelial brushing eotaxins in chronic asthma. Authors conclude that eotaxin-2 and -3 may contribute to luminal migration of eosinophils.1 However, potential roles of such transepithelial cell traffic are not discussed. In a recent editorial, Rosenberg highlights the possibility that luminal migration of eosinophils importantly eliminates these cells from diseased bronchial tissues.2 (Coleman et al 1 cite an earlier review by Rosenberg et al, dealing …