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Thalidamide for IPF-associated cough
  1. Peter Kardos
  1. Correspondence to Dr Peter Kardos, Group Practice and Respiratory, Allergy and Sleep Unit at Red Cross Maingau Hospital, Scheffelstrasse 33, Frankfurt 60318, Germany; Kardos{at}Lungepraxis-Maingau.de

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This small, randomised twelve-week crossover trial based at Johns Hopkins in Baltimore, USA, assessed the efficacy of thalidomide versus placebo on cough in patients with idiopathic pulmonary fibrosis (IPF). This drug when previously given as Contergan for hyperemesis gravidarum led to birth defects; however, it is now approved for the treatment of refractory multiple myeloma and …

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