Proteolytic activity in cowshed dust extracts induces C5a release in murine bronchoalveolar lavage fluids which may account for its protective properties in allergic airway inflammation

Matthias Stiehm; Albrecht Bufe; Marcus Peters

doi:10.1136/thoraxjnl-2012-201746

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Asthma and the environment

Proteolytic activity in cowshed dust extracts induces C5a release in murine bronchoalveolar lavage fluids which may account for its protective properties in allergic airway inflammation

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	Abstract	Full	Pdf
Oct 2012	173	7	16
Nov 2012	156	21	13
Dec 2012	758	9	37
Jan 2013	883	15	27
Feb 2013	324	15	13
Mar 2013	213	12	7
Apr 2013	132	6	9
May 2013	101	6	5
Jun 2013	100	4	4
Jul 2013	61	6	6
Aug 2013	48	6	6
Sep 2013	36	4	5
Oct 2013	58	14	7
Nov 2013	30	9	17
Dec 2013	30	5	4
Jan 2014	32	8	4
Feb 2014	40	6	5
Mar 2014	46	11	4
Apr 2014	42	10	8
May 2014	34	7	7
Jun 2014	19	2	6
Jul 2014	28	15	10
Aug 2014	13	13	1
Sep 2014	17	4	4
Oct 2014	22	1	2
Nov 2014	11	3	1
Dec 2014	15	3	4
Jan 2015	11	0	0
Feb 2015	6	2	1
Mar 2015	30	2	1
Apr 2015	11	3	3
May 2015	15	1	0
Jun 2015	26	3	4
Jul 2015	10	1	0
Aug 2015	11	1	2
Sep 2015	18	1	2
Oct 2015	9	4	1
Nov 2015	11	6	3
Dec 2015	8	4	6
Jan 2016	3	9	11
Feb 2016	20	16	5
Mar 2016	4	4	12
Apr 2016	13	8	11
May 2016	20	7	12
Jun 2016	10	14	20
Jul 2016	19	10	20
Aug 2016	11	7	14
Sep 2016	17	10	15
Oct 2016	34	11	14
Nov 2016	23	12	10
Dec 2016	23	10	13
Jan 2017	18	4	6
Feb 2017	7	11	11
Mar 2017	0	14	13
Apr 2017	1	24	11
May 2017	3	21	10
Jun 2017	5	18	9
Jul 2017	16	15	13
Aug 2017	20	16	11
Sep 2017	26	24	9
Oct 2017	22	18	13
Nov 2017	40	34	11
Dec 2017	31	25	11
Jan 2018	27	27	19
Feb 2018	33	27	12
Mar 2018	25	25	18
Apr 2018	24	22	20
May 2018	30	29	12
Jun 2018	35	33	18
Jul 2018	27	23	25
Aug 2018	31	31	21
Sep 2018	27	27	22
Oct 2018	24	24	27
Nov 2018	28	28	40
Dec 2018	21	21	20
Jan 2019	21	19	30
Feb 2019	23	22	38
Mar 2019	22	22	30
Apr 2019	21	16	28
May 2019	25	26	42
Jun 2019	20	20	47
Jul 2019	17	15	33
Aug 2019	21	21	47
Sep 2019	17	17	53
Oct 2019	23	21	36
Nov 2019	21	17	29
Dec 2019	13	11	26
Jan 2020	23	19	30
Feb 2020	14	13	36
Mar 2020	17	13	34
Apr 2020	5	3	5
May 2020	9	5	6
Jun 2020	6	6	3
Jul 2020	11	7	3
Aug 2020	7	4	9
Sep 2020	33	19	3
Oct 2020	15	13	7
Nov 2020	17	16	8
Dec 2020	14	10	5
Jan 2021	15	15	7
Feb 2021	15	14	11
Mar 2021	19	17	11
Apr 2021	23	19	6
May 2021	32	33	13
Jun 2021	72	71	14
Jul 2021	40	40	22
Aug 2021	44	44	15
Sep 2021	21	20	17
Oct 2021	8	8	30
Nov 2021	13	13	24
Dec 2021	12	11	4
Jan 2022	8	8	5
Feb 2022	10	10	5
Mar 2022	12	12	6
Apr 2022	14	13	10
May 2022	24	23	27
Jun 2022	21	21	16
Jul 2022	25	19	4
Aug 2022	25	25	6
Sep 2022	29	25	22
Oct 2022	48	43	10
Nov 2022	12	12	8
Dec 2022	5	5	3
Jan 2023	10	5	2
Feb 2023	29	29	4
Mar 2023	3	3	1
Apr 2023	2	2	1
May 2023	4	4	10
Jun 2023	9	9	4
Jul 2023	10	10	6
Aug 2023	12	10	28
Sep 2023	9	7	18
Oct 2023	47	41	1
Nov 2023	11	9	1
Dec 2023	27	27	4
Jan 2024	6	6	2
Feb 2024	8	8	4
Mar 2024	7	6	90
Total	5462	1961	1854

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