S126 Interleukin-1 Alpha (IL-1α) Released from Injured Lung Epithelium is a Critical Alarmin Driving Activation of a Potent Inflammatory Phenotype in Lung Fibroblasts

MI Suwara; LA Borthwick; R Mahida; NJ Green; K Mayer-Barber; A Gardner; J Mann; TA Wynn; PA Corris; SN Farrow; DA Mann; AJ Fisher

doi:10.1136/thoraxjnl-2012-202678.131

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Novel mechanisms in lung fibrogenesis

S126 Interleukin-1 Alpha (IL-1α) Released from Injured Lung Epithelium is a Critical Alarmin Driving Activation of a Potent Inflammatory Phenotype in Lung Fibroblasts

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MI Suwara 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
LA Borthwick 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
R Mahida 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
NJ Green 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
K Mayer-Barber 2Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA PubMed articles Google scholar articles
A Gardner 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
J Mann 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
TA Wynn 2Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA PubMed articles Google scholar articles
PA Corris 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
SN Farrow 3Respiratory therapy area, GlaxoSmithKline, Stevenage, United Kingdom PubMed articles Google scholar articles
DA Mann 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles
AJ Fisher 1Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Newcastle University, United Kingdom PubMed articles Google scholar articles

Citation

Suwara M, Borthwick L, Mahida R, et al

S126 Interleukin-1 Alpha (IL-1α) Released from Injured Lung Epithelium is a Critical Alarmin Driving Activation of a Potent Inflammatory Phenotype in Lung Fibroblasts

Thorax 2012;67:A60-A61.

Publication history

First published November 19, 2012.

Online issue publication

September 01, 2022

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