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Mouse lung regeneration after H1N1
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This study demonstrates that following an ARDS-like syndrome in mice secondary to infection with a murine-adapted H1N1 virus, complete recovery follows the emergence of a population of stem cells bearing the differentiation markers of alveoli.
Contrary to the existing bleomycin-based models of pulmonary injury causing fibrosis, this murine H1N1 model sustains substantial airway damage and epithelial destruction, followed by …