Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

Paul Albert; Alvar Agusti; Lisa Edwards; Ruth Tal-Singer; Julie Yates; Per Bakke; Bartolome R Celli; Harvey O Coxson; Courtney Crim; David A Lomas; William MacNee; Bruce Miller; Stephen Rennard; Edwin K Silverman; Jørgen Vestbo; Emiel Wouters; Peter Calverley

doi:10.1136/thoraxjnl-2011-201458

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Chronic obstructive pulmonary disease

Original article

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

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Jun 2012	554	71	167
Jul 2012	1219	77	203
Aug 2012	1026	126	276
Sep 2012	415	59	97
Oct 2012	357	103	98
Nov 2012	264	48	66
Dec 2012	193	22	40
Jan 2013	165	54	52
Feb 2013	111	21	30
Mar 2013	196	20	38
Apr 2013	144	35	46
May 2013	117	23	27
Jun 2013	78	19	22
Jul 2013	50	19	15
Aug 2013	67	12	28
Sep 2013	52	17	19
Oct 2013	73	12	20
Nov 2013	65	30	28
Dec 2013	40	22	25
Jan 2014	59	21	28
Feb 2014	66	12	16
Mar 2014	116	29	34
Apr 2014	62	21	27
May 2014	63	14	15
Jun 2014	36	13	16
Jul 2014	65	22	27
Aug 2014	30	9	11
Sep 2014	61	14	21
Oct 2014	50	11	14
Nov 2014	63	12	16
Dec 2014	29	2	3
Jan 2015	23	14	11
Feb 2015	29	14	14
Mar 2015	44	18	16
Apr 2015	23	17	13
May 2015	34	13	15
Jun 2015	47	11	16
Jul 2015	54	13	17
Aug 2015	12	18	27
Sep 2015	34	29	27
Oct 2015	24	18	18
Nov 2015	21	34	38
Dec 2015	25	24	37
Jan 2016	41	28	30
Feb 2016	22	19	24
Mar 2016	19	21	35
Apr 2016	29	34	36
May 2016	43	30	26
Jun 2016	21	34	31
Jul 2016	30	31	35
Aug 2016	21	23	23
Sep 2016	46	42	26
Oct 2016	35	35	32
Nov 2016	55	34	37
Dec 2016	23	38	21
Jan 2017	36	46	23
Feb 2017	14	30	21
Mar 2017	7	42	35
Apr 2017	3	43	21
May 2017	4	64	24
Jun 2017	11	49	8
Jul 2017	40	39	19
Aug 2017	74	62	58
Sep 2017	65	59	25
Oct 2017	52	46	23
Nov 2017	69	63	28
Dec 2017	73	61	22
Jan 2018	46	42	21
Feb 2018	60	49	26
Mar 2018	68	62	67
Apr 2018	57	57	44
May 2018	49	47	34
Jun 2018	42	38	31
Jul 2018	48	38	28
Aug 2018	58	44	22
Sep 2018	30	28	24
Oct 2018	27	27	16
Nov 2018	43	33	70
Dec 2018	40	32	38
Jan 2019	40	30	33
Feb 2019	40	35	30
Mar 2019	33	24	33
Apr 2019	34	28	53
May 2019	49	45	78
Jun 2019	42	39	63
Jul 2019	43	44	70
Aug 2019	37	37	34
Sep 2019	32	28	34
Oct 2019	46	44	57
Nov 2019	34	30	70
Dec 2019	72	70	95
Jan 2020	38	31	33
Feb 2020	46	44	35
Mar 2020	31	29	20
Apr 2020	83	80	53
May 2020	35	30	23
Jun 2020	29	23	21
Jul 2020	54	39	24
Aug 2020	33	29	21
Sep 2020	194	184	19
Oct 2020	64	56	24
Nov 2020	25	21	19
Dec 2020	32	23	37
Jan 2021	43	39	49
Feb 2021	38	34	47
Mar 2021	30	20	36
Apr 2021	48	36	28
May 2021	40	37	31
Jun 2021	37	37	25
Jul 2021	23	23	26
Aug 2021	30	29	28
Sep 2021	54	54	35
Oct 2021	43	37	44
Nov 2021	60	52	68
Dec 2021	39	35	26
Jan 2022	38	39	30
Feb 2022	48	46	36
Mar 2022	63	56	45
Apr 2022	72	48	26
May 2022	85	64	53
Jun 2022	62	55	30
Jul 2022	57	44	18
Aug 2022	65	57	35
Sep 2022	57	53	46
Oct 2022	55	51	44
Nov 2022	62	51	26
Dec 2022	56	42	19
Jan 2023	57	49	18
Feb 2023	34	31	18
Mar 2023	42	38	22
Apr 2023	61	49	39
May 2023	66	56	36
Jun 2023	48	42	19
Jul 2023	49	50	23
Aug 2023	70	62	31
Sep 2023	54	53	21
Oct 2023	47	46	25
Nov 2023	73	64	13
Dec 2023	91	80	15
Jan 2024	95	71	14
Feb 2024	87	63	26
Mar 2024	72	64	163
Apr 2024	160	143	56
May 2024	249	198	32
Jun 2024	214	17	7
Jul 2024	199	19	5
Aug 2024	144	13	5
Sep 2024	78	7	2
Total	12018	5960	5278

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