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Helicobacter pylori infection in neonatal mice prevents allergic asthma
  1. Nawaid Ahmad
  1. Correspondence toDr Nawaid Ahmad, ST5 Respiratory Medicine. University Hospitals North Staffordshire, Newcastle Road, Stoke-on-trent, ST4 6QG, UK; navvydoc{at}gmail.com

https://doi.org/10.1136/thoraxjnl-2011-201061

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    In this preclinical study, the authors hypothesised that neonatal infection with an immonomodulatory pathogen such as Helicobacter pylori provides protection from allergic airway inflammation and hyper-responsiveness seen in allergic asthma.

    C57BL/6 mice were orally infected with H pylori at 6 days (neonatal) and 6 weeks (adults) after birth. Infected and non-infected mice underwent …

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