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Research update
Pulmonary metastasectomy in colorectal cancer: the PulMiCC trial
  1. Tom Treasure1,
  2. Lesley Fallowfield2,
  3. Belinda Lees3,
  4. Vern Farewell4
  1. 1Clinical Operational Research Unit, Department of Mathematics, University College London, London, UK
  2. 2Cancer Research UK Psychosocial Oncology, Brighton & Sussex Medical School, University of Sussex, Brighton, UK
  3. 3Clinical Trials and Evaluation Unit, Royal Brompton Hospital, London, UK
  4. 4MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, UK
  1. Correspondence to Tom Treasure, Clinical Operational Research Unit, Department of Mathematics, University College London, 4 Taviton Street, London WC1H 0BT, UK; tom.treasure{at}


PulMiCC (Pulmonary Metastasectomy in Colorectal Cancer) is a randomised controlled trial funded by Cancer Research UK. Patients with a history of resected colorectal cancer who are found to have pulmonary metastases are first registered for evaluation and, if subsequently eligible for the trial, they are invited to be randomly allocated to ‘active monitoring’ or ‘active monitoring with pulmonary metastasectomy’. The clinical outcomes are overall survival, relapse-free survival, lung function and patient-reported quality of life.

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  • Funding Cancer Reasearch UK.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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