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Correspondence
Use of sputum eosinophil counts to guide management in children with severe asthma
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  1. Louise Fleming,
  2. Andrew Bush
  1. Department of Respiratory Paediatrics, Royal Brompton Hospital, London, UK
  1. Correspondence to Dr Louise Fleming, Department of Respiratory Paediatrics, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK; l.fleming{at}imperial.ac.uk

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We thank Professors Pavord and Gibson for their commentary on our study investigating sputum eosinophil counts as a guide to management in children with severe asthma.1 ,2 They suggest two important reasons for our negative results: (1) the protocol was not followed and (2) the protocol was incorrect. For the most part (95% of study visits), the protocol was followed …

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