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Letter to the Editor
Outcomes following non-invasive ventilation for hypercapnic exacerbations of chronic obstructive pulmonary disease
  1. Iain Murray1,
  2. Ed Paterson1,
  3. Gillian Thain2,
  4. Graeme P Currie1
  1. 1Chest Clinic C, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK
  2. 2Physiotherapy Unit, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK
  1. Correspondence to Graeme P Currie, Chest Clinic C, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland AB25 2DZ, UK; graeme.currie{at}nhs.net

https://doi.org/10.1136/thx.2010.152264

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    Many carefully crafted studies with different end points have shown significant benefits with non-invasive ventilation (NIV) over and above conventional medical treatment alone in the management of hypercapnic exacerbations of chronic obstructive pulmonary disease (COPD).1 However, most data have evaluated highly selected patients within stringent realms of randomised controlled trials. Since strict criteria need to be fulfilled before clinical trial entry (often excluding elderly patients and those with major co-morbidities, electrolyte disturbance and severe exacerbations), outcomes may not be reflective of everyday practice. We wished to highlight demographics, physiological variables, outcomes and 1-year survival in a large cohort of patients receiving ward-based NIV for hypercapnic exacerbations …

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    Footnotes

    • Competing interests None.

    • Provenance and peer review Not commissioned; externally peer reviewed.