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CFTR-knockout neonatal ferrets model may be useful in the understanding of CF pathogenesis and developing therapies
  1. Albert YH Lim
  1. North West Midlands Cystic Fibrosis Centre, University Hospital of North Staffordshire, Stoke on trent, UK
  1. Correspondence to Dr Albert YH Lim, North West Midlands Cystic Fibrosis Centre, University Hospital of North Staffordshire, UK; albert.lim{at}uhns.nhs.uk

https://doi.org/10.1136/thx.2010.151910

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    There is no adequate animal model of cystic fibrosis (CF) airways disease. This study investigated using CFTR-knockout neonatal ferrets as they show similarities to newborn humans with CF. These similarities include meconium ileus (MI), pancreatic disease, liver disease, …

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