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Transbronchial needle aspiration in the diagnosis of mediastinal amyloidosis
  1. Virginia Leiro-Fernández,
  2. Maribel Botana-Rial,
  3. Cristina Represas,
  4. Alberto Fernández-Villar
  1. Investigation Group in Respiratory and Infectious diseases, Pulmonary Department, Complejo Hospitalario Universitario Vigo (CHUVI), Instituto de investigación Biomédica Vigo (IBIV), Spain
  1. Correspondence to Virginia Leiro-Fernández, Pulmonary Department, Complejo Hospitalario Universitario de Vigo c/ Pizarro, n 22. 36204 Vigo, Pontevedra, Spain; virginia.leiro.fernandez{at}

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We read with interest the pulmonary puzzle by Khor et al1 on mediastinal lymph node amyloidosis diagnosed by direct real-time endobronchial ultrasound-guided (EBUS) transbronchial needle aspiration (TBNA). The development of EBUS-TBNA is improving the diagnostic yield of mediastinal lymphadenopathy.2 However, we offer some comments about the diagnostic approach used in the case described.

First, in our opinion, conventional TBNA continues …

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; not externally peer reviewed.