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Vitamin D and COPD: seasonal variation is important
  1. Sundari N Ampikaipakan1,
  2. David A Hughes2,
  3. Jackie C Hughes2,
  4. Talar Amen1,
  5. Graham Bentham3,
  6. Andrew M Wilson3
  1. 1Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk, UK
  2. 2Institute of Food Research, Norwich, Norfolk, UK
  3. 3University of East Anglia, Norwich, Norfolk, UK
  1. Correspondence to Dr S N Ampikaipakan, Department of Respiratory Medicine, Norfolk and Norwich University Hospitals NHS Foundation Trust, Level 3 East Block, Colney Lane, Norwich NR4 7UY, UK; sundari.ampi{at}

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Janssens et al1 have demonstrated the relationship between vitamin D status and lung function in patients with chronic obstructive pulmonary disease (COPD). However, in their study there was only one assessment of vitamin D status per patient. Given the minimal component of diet to vitamin D status (serum 25-hydroxyvitamin D (25(OH)D) concentration),2 it is mostly determined by sunlight exposure and has a seasonal variation in healthy individuals.3

In a study of 24 patients with COPD (mean (SD) age 69 (5.8) years and smoking history 43 (15.8) pack-years) with measurements undertaken in the same individuals at the end of summer (August/September) and winter (March/April), we …

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  • Competing interests None.

  • Ethics approval This study was conducted with the approval of the Norfolk research ethics committee.

  • Provenance and peer review Not commissioned; not externally peer reviewed.