Article Text

Download PDFPDF

Nocturnal monitoring of home non-invasive ventilation: the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software and autonomic markers of sleep fragmentation
  1. Jean-Paul Janssens1,
  2. Jean-Christian Borel2,3,
  3. Jean-Louis Pépin2,
  4. on behalf of the SomnoNIV Group
  1. 1Division of Pulmonary Diseases, Geneva University Hospital, Geneva, Switzerland
  2. 2Pole Rééducation et Physiologie et Laboratoire HP2, INSERM ERI 0017, Université Joseph Fourier, Grenoble, France
  3. 3Association médico-technique AGIR à dom, Meylan, France
  1. Correspondence to Jean Paul Janssens, Centre Antituberculeux, Division of Pulmonary Diseases, Geneva University Hospital, Rue Gabrielle Perret-Gentil 4, 1211 Geneva 14, Switzerland; jean-paul.janssens{at}


Complex respiratory events, which may have a detrimental effect on both quality of sleep and control of nocturnal hypoventilation, occur during sleep in patients treated with non-invasive ventilation (NIV). Among these events are patient-ventilator asynchrony, increases in upper airway resistance (with or without increased respiratory drive) and leaks. Detection of these events is important in order to select the most appropriate ventilator settings and interface. Simple tools can provide important information when monitoring NIV. Pulse oximetry is important to ensure that adequate oxygen saturation is provided and to detect either prolonged or short and recurrent desaturations. However, the specificity of pulse oximetry tracings during NIV is low. Transcutaneous capnography helps discriminate between hypoxaemia related to ventilation/perfusion mismatch and hypoventilation, documents correction of nocturnal hypoventilation and may detect ventilator-induced hyperventilation, a possible cause for central apnoea/hypopnoea and glottic closure. Data provided by ventilator software help the clinician by estimating ventilation, tidal volume, leaks and the rate of inspiratory or expiratory triggering by the patient, although further validation of these signals by independent studies is indicated. Finally, autonomic markers of sympathetic tone using signals such as pulse wave amplitude of the pulse oximetry signal can provide reliable information of sleep fragmentation.

  • Non invasive ventilation
  • respiratory muscles
  • sleep apnoea
View Full Text

Statistics from


  • Linked articles 142661, 142653.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles