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Miscellanea
Journal club
Genetic variants and risk of lung cancer in never smokers
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  1. Abbey Leahy
  1. Correspondence to Abbey Leahy, Respiratory SpR, United Bristol Hospital NHS Foundation Trust, Bristol BS1 3NU, UK; abbey.leahy{at}UHBristol.nhs.uk

https://doi.org/10.1136/thx.2010.145581

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    This four-stage study systematically investigated common genetic variations associated with the risk of developing lung cancer in never smokers. Stage 1 involved a genome-wide association study at the Mayo Clinic. A total of 331 918 single nucleotide polymorphisms (SNPs) in 377 case–control matched pairs were analysed. The 44 most significant SNPs that might alter the risk of …

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