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  • The inhibition of anaplastic lymphoma kinase in non-small cell lung tumours with the ALK rearrangement may result in tumour shrinkage

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The inhibition of anaplastic lymphoma kinase in non-small cell lung tumours with the ALK rearrangement may result in tumour shrinkage
  1. Louise Hancock
  1. Correspondence to Dr Louise Hancock, North Middlesex Hospital, London, UK; lhancock{at}doctors.org.uk

https://doi.org/10.1136/thx.2011.159467

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    In this study, the therapeutic efficacy of inhibiting anaplastic lymphoma kinase (ALK) in oncogenic fusion genes consisting of EML4 and ALK was explored in an early-phase clinical trail of crizotinib. Tumour samples from 1500 patients with non-small cell lung cancer (NSCLC) …

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