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  1. Michaela Lucas1,
  2. Pam Nicol2,
  3. Elizabeth McKinnon3,
  4. Rebecca Whidborne1,
  5. Andrew Lucas3,
  6. Aesen Thambiran4,
  7. David Burgner5,
  8. Justin Waring6,
  9. Martyn French7
  1. 1Department of Clinical Immunology, Royal Perth Hospital and Pathwest Laboratory Medicine, Perth, Western Australia
  2. 2School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia
  3. 3Centre for Clinical Immunology and Biomedical Statistics, Murdoch University, Perth, Western Australia
  4. 4Migrant Health Unit, North Metropolitan Area Health Service, Perth, Western Australia
  5. 5Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia
  6. 6TB Control Program, North Metropolitan Area Health Service, Perth, Western Australia
  7. 7School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia
  1. Correspondence to Michaela Lucas, Royal Perth Hospital and Pathwest Laboratory Med, Wellington Street, Perth, 6000 Australia; michaela.lucas{at}health.wa.gov.au

https://doi.org/10.1136/thx.2010.149732

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    The commentary by Connell et al1 on the data presented in our paper2 is a welcome contribution to the debate on the most appropriate method for demonstrating latent tuberculosis (TB) infection in refugee children. Although a comparison of the performance of interferon-γ release assays (IGRAs) with tuberculin skin tests (TSTs) was not the primary aim of our study, the data do allow us to make observations on this topic. We have reassessed our data on the effect of previous BCG immunisation on IGRA and TST positivity (see table 3) and suggest that the very similar ORs for IGRAs and TST might reflect the adjustment of the cut-off point for a positive TST where we had added 5 mm for children under the age …

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    Footnotes

    • Linked article 143396.

    • Competing interests None.

    • Provenance and peer review Not commissioned; not externally peer reviewed.

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