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  1. Jian-Qing He1,
  2. Loubna Akhabir1,
  3. Don D Sin1,
  4. S F Paul Man1,
  5. Peter D Paré1,
  6. Andrew J Sandford1,
  7. Marilyn G Foreman2,3,
  8. Dawn L DeMeo2,3,
  9. Edwin K Silverman2,3
  1. 1The UBC James Hogg Research Center, St Paul's Hospital, University of British, Columbia, Vancouver, BC, Canada
  2. 2Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
  3. 3Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
  1. Correspondence to Jian-Qing He, UBC James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, University of BC, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada; jhe{at}mrl.ubc.ca
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http://dx.doi.org/10.1136/thx.2010.149658

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    van den Borst and colleagues present interesting data regarding the role of the interleukin 6 (IL6)-74G/C promoter polymorphism (rs1800795) in determining the level of lung function.1 We have shown that the C allele of the -174 polymorphism was associated with more rapid decline of lung function in the Lung Health Study (LHS) and with chronic …

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