Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?
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We read with interest the recent paper by Facco et al which showed that Th17 cells are present in blood, bronchoalveolar lavage (BAL) and lung tissue from people with sarcoidosis. The authors conclude that Th17 cells are involved in the pathogenesis of sarcoidosis as a multisystem disorder.1
Interestingly, the paper mentions expression of interleukin (IL)-17 protein by macrophages. Currently, a strong emphasis exists in the literature …