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Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?
  1. Malcolm Brodlie1,2,
  2. James Lordan1,3,
  3. Christopher Ward1
  1. 1Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
  2. 2Department of Respiratory Paediatrics, Great North Children's Hospital, Newcastle upon Tyne, UK
  3. 3Cardiopulmonary Transplantation Unit, Freeman Hospital, Newcastle upon Tyne, UK
  1. Correspondence to Dr Malcolm Brodlie, c/o Paediatric Respiratory Secretaries, Old Children's Outpatients Department, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK; m.j.brodlie{at}

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We read with interest the recent paper by Facco et al which showed that Th17 cells are present in blood, bronchoalveolar lavage (BAL) and lung tissue from people with sarcoidosis. The authors conclude that Th17 cells are involved in the pathogenesis of sarcoidosis as a multisystem disorder.1

Interestingly, the paper mentions expression of interleukin (IL)-17 protein by macrophages. Currently, a strong emphasis exists in the literature …

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  • Linked articles 159558.

  • Funding Medical Research Council, Cystic Fibrosis Trust.

  • Competing interests None.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

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