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  1. Carl G Persson1,
  2. Lena Uller2
  1. 1Department of Clinical Pharmacology, Laboratory Medicine, Lund University Hospital, Lund, Sweden
  2. 2Department of Experimental Medical Science, Lund University, Lund, Sweden
  1. Correspondence to Professor Carl G Persson, Department of Clinical Pharmacology, Laboratory Medicine, Lund University Hospital, Lund, Sweden; carl.persson{at}med.lu.se

https://doi.org/10.1136/thx.2010.158220

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    We obviously agree with Porter1 on the need to make a distinction between egression of infiltrated leucocytes across mucosal epithelia, where a swift further elimination of the lumen cells can be expected to occur (nasal, tracheobronchial, gut, bladder), and the bronchiolar–alveolar epithelial linings where there is a risk of undesirable accumulation of lumen cells. We repeat this cautionary note in an extended review on resolution of cell-mediated respiratory diseases where we discuss a role of egression in the elimination not only of granulocytes and lymphocytes but also of mast cells and dendritic cells.2 We further discuss how elimination of leucocytes through egression can be compatible …

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    Footnotes

    • Linked article 157065.

    • Funding From Swedish Medical Research Council.

    • Competing interests None.

    • Provenance and peer review Not commissioned; not externally peer reviewed.

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