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Single maintenance and reliever therapy (SMART) of asthma
  1. Helen K Reddel1,2,
  2. Kwok Y Yan2
  1. 1Woolcock Institute of Medical Research, Sydney, Australia
  2. 2Royal Prince Alfred Hospital, Camperdown, Australia
  1. Correspondence to Helen Reddel, Associate Professor, Woolcock Institute of Medical Research, P O Box M77, Missenden Rd Post Office, NSW 2050, Australia; hkr{at}

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We write to raise concerns about the recent paper by Chapman et al on single maintenance and reliever therapy (SMART) of asthma,1 on the basis that it misrepresents published scientific evidence. The errors include:

  1. Reporting outcome measures for one treatment arm from several double-blind studies (table 1 and accompanying text), but omitting the published data2 for comparator arms from the same studies which would have been highly relevant …

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  • Competing interests HR has received research funding from GlaxoSmithKline and AstraZeneca and honoraria for consulting, participation on advisory boards and/or continuing medical education presentations from AstraZeneca, GlaxoSmithKline, Merck, Getz, Novartis, Biota and Boehringer Ingelheim. KY has received honoraria from GlaxoSmithKline, AstraZeneca, Nycomed and Schering Plough for lectures and participation on advisory boards.

  • Provenance and peer review Not commissioned; not externally peer reviewed.

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