Can procalcitonin have a role in reducing antibiotic selective pressure? | Thorax

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Can procalcitonin have a role in reducing antibiotic selective pressure?

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S Pomfret

Correspondence to Dr S Pomfret, Core Medical Trainee, Homerton University Hospital, London E9 6SR, UK; suzanne.pomfret{at}homerton.nhs.uk

https://doi.org/10.1136/thx.2010.145516

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This multicentre, prospective, parallel group randomised trial compared the use of a modified previously published procalcitonin-guided algorithm for antibiotic use with the conventional use of local or national guidelines for antibiotic use over seven intensive care units. A total of 307 patients in the procalcitonin group and 314 in the control group were included. In …