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IL-23 and allergic airway inflammation
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This study examines the role of interleukin 23 (IL-23) in airway inflammation in asthma, focusing on the ability of IL-23 to promote inflammation independently of the known IL-17 pathway and via its effect on T helper 2 (Th2) polarisation. These interactions are studied using in vitro and in vivo techniques.
Mice exposed to allergen showed a significant …