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IL-23 and allergic airway inflammation
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  1. Charlotte Addy
  1. Correspondence to Charlotte Addy, ST4, Bristol Royal Infirmary, UK; chill1981{at}doctors.org.uk

https://doi.org/10.1136/thx.2010.141101

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    This study examines the role of interleukin 23 (IL-23) in airway inflammation in asthma, focusing on the ability of IL-23 to promote inflammation independently of the known IL-17 pathway and via its effect on T helper 2 (Th2) polarisation. These interactions are studied using in vitro and in vivo techniques.

    Mice exposed to allergen showed a significant …

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